Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 2.1 (5-Year IF – 2.0)
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Index Copernicus  – 171.00; MNiSW – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2017, vol. 26, nr 8, November, p. 1293–1300

Publication type: review

Language: English

Valve bladder syndrome in children: On the trail of the best strategies to prevent chronic kidney disease

Dorota Polak-Jonkisz1,A,B,D,E,F, Leopold R. Rehan2,B,D, Konstancja Fornalczyk1,A,B, Paweł Hackemer3,B,D, Danuta Zwolińska1,A,E,F

1 Department of Pediatric Nephrology, Wroclaw Medical University, Poland

2 Department of Internal Medicine, Occupational Diseases and Hypertension, Medical University Hospital, Wrocław, Poland

3 Department of Urolody, Medical University Hospital, Wrocław, Poland

Abstract

Pediatric patients suffering from valve bladder syndrome (VBS) are at risk of developing chronic kidney disease (CKD) and renal failure in later life. Therefore, it is of vital importance to determine the risk factors and the best possible strategies for diagnosis and treatment in patients with VBS that would minimize the risk of developing CKD. In this review we have presented the current knowledge of CKD risk factors in patients with posterior urethal value (PUV). We have also discussed possible recommendations for prenatal diagnostics procedures to be undertaken in patients with PUV, postnatal monitoring and therapeutic strategies that could reduce the risk of developing CKD in this population. Although in most cases there are no clear guidelines for appropriate clinical actions that can be undertaken in patients with PUV to minimize the risk of kidney failure, we have tried to present concise and accurate advice for physicians taking care of patients with PUV.

Key words

chronic kidney disease, valve bladder syndrome, bladder dysfunction, posterior urethral valve

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