Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 1.727
Index Copernicus  – 166.39
MEiN – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2015, vol. 24, nr 6, November-December, p. 1113–1117

doi: 10.17219/acem/50572

Publication type: review article

Language: English

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Mycotic Infections of the Eye

Mirosław Słowik1,A,D, Monika M. Biernat2,3,B,D, Donata Urbaniak-Kujda3,B,E, Katarzyna Kapelko-Słowik3,A,B,D, Marta Misiuk-Hojło1,F

1 Department and Clinic of Ophthalmology, Wroclaw Medical University, Poland

2 Department of Microbiology, Wroclaw Medical University, Poland

3 Department and Clinic of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Poland

Abstract

Fungal infections of the eye are an important cause of significant visual loss and blindness in some regions of the world, especially developing countries. Ocular mycoses remain a diagnostic and therapeutic challenge to the ophthalmologist. Corneal infection is the most frequent presentation, but the orbit, eyelids, lacrimal apparatus, conjunctiva, sclera and internal structures of the eye can also be affected. Candida spp., Fusarium spp. and Aspergillus spp. are the most frequently isolated organisms in fungal keratitis and in endophthalmitis. The difficulties posed by ocular mycoses are mainly related to establishing the clinical diagnosis, isolation of the fungal pathogen and effective local treatment, particularly in infections of the cornea. The critical issue in diagnosing fungal infection of the eye is microbiological identification of the etiologic agent in clinical samples. Early diagnosis and prompt treatment allow serious complications, including blindness, to be avoided. Local, systemic and even surgical treatment is applied in the therapy.

Key words

ocular mycoses, fungal keratitis, antifungal drugs

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