Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 1.736
5-Year Impact Factor – 2.135
Index Copernicus  – 168.52
MEiN – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2015, vol. 24, nr 3, May-June, p. 505–509

doi: 10.17219/acem/36600

Publication type: original article

Language: English

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Transurethral Resection of the Bladder Tumour as a Treatment Method in Children with Transitional Cell Carcinoma of the Bladder – Analysis of Our Material and Literature Review

Wojciech Apoznański1,A,B,C,D,E,F, Jolanta Rysiakiewicz1,A,B,C,D,E,F, Marcin Polok1,A,B,C,D,E,F, Konrad Rysiakiewicz1,A,B,C,D,E,F, Piotr Siekanowicz1,A,B,C,D,E,F, Tomasz Hilger2,A,B,C,D,E,F, Jan Zagierski2,A,B,C,D,E,F, Magdalena Hilger3,A,B,C,D,E,F, Irena Nowak3,A,B,C,D,E,F, Piotr Kolęda4,A,B,C,D,E,F, Tomasz Szydełko5,A,B,C,D,E,F

1 Department of Paediatric Surgery and Urology, Wroclaw Medical University, Poland

2 Department of Paediatric Surgery and Traumatology, Bieganski Regional Specialist Hospital, Grudziądz, Poland

3 Department of Paediatry, Bieganski Regional Specialist Hospital, Grudziądz, Poland

4 Department of Pathophysiology, Wroclaw Medical University, Poland

5 Department of Palliative Care Nursing, Wroclaw Medical University, Poland Department of Urology, 4th Military Clinical Hospital with Polyclinic, Wrocław, Poland

Abstract

Background. Bladder cancer occurs mainly in adults. In children, younger than 10 years in particular, it is very rare.
Objectives. The aim of the study is to retrospectively evaluate the efficacy of transurethral resection of the bladder tumour (TUR-BT) of transitional cell carcinoma (TCC) of the bladder in children.
Material and Methods. Transurethral resection of the bladder tumour was performed in 7 boys aged 4 to 17 years (median 12.1 years). In all cases laboratory tests, ultrasound, and cystoscopic tumour biopsy were carried out prior to the resection. Doxorubicin was additionally instilled intravesically as one dose in two patients. The Foley catheter was left in the bladder for 1 to 4 days (median 1.85 days). The follow-up period ranged from 10 months to 10 years (median 4 years).
Results. Papillary urothelial neoplasm of low malignant potential (PUNLMP) was diagnosed in 5 patients and urothelial papilloma in 2. Local recurrence was observed in one case two years after the resection. In all other cases complete remission was achieved.
Conclusion. Transitional cell carcinoma of the bladder in children is usually benign and endoscopic treatment (TUR-BT) seems to be the treatment of choice. To determine a follow-up schedule a more substantial group of children with bladder cancer should be analysed.

Key words

children, TCC, bladder tumor, transitional cell carcinoma, haematuria.

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