Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 1.736
5-Year Impact Factor – 2.135
Index Copernicus  – 168.52
MEiN – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2014, vol. 23, nr 5, September-October, p. 763–768

Publication type: original article

Language: English

A Comparison of Pre-Operative Nutritional Status with Post-Operative Morbidity and Mortality in Obese Esophageal Surgery Patients

Subhamay Ghosh1,2,A,D,E,F, Balázs Ittzés1,3,B,C, Lajos Bogár1,B,D, Tamás Kõszegi4,B,C, Péter Örs Horváth5,B,D, Lászlo Cseke5,C,D, András Papp5,C,D, Sándor Márton1,2,A,D,E,F

1 Department of Anaesthesiology and Intensive Therapy, University of Pécs, Hungary

2 Department of Anaesthesia and Perioperative Medicine, St. Boniface Hospital, University of Manitoba, Winnipeg, Canada.

3 Department of Anaesthesia, North Devon District Hospital, Barnstaple, UK

4 Department of Laboratory Medicine, University of Pécs, Hungary

5 Department of Surgery, University of Pécs, Hungary


Objectives. The nutrition state of obese patients scheduled to undergo esophageal surgery was evaluated using two nutritional score systems: the mini nutritional assessment (MNA) and the prognostic and nutritional index (PINI). A further comparison of various proteins, lymphocytes and cholesterol was performed using biochemical tests. These factors were compared with post-operative morbidity and mortality in a prospective, descriptive clinical study.
Material and Methods. The study included 34 obese patients undergoing esophagus resection due to cancer, who were examined over four years using both scoring systems to analyze whether nutritional status influences the outcome of surgery. The patients were divided into four groups based on the severity of the outcome and their MNA and PINI scores were analyzed.
Results. There were no significant differences between the nutritional status of survivors and deceased patients. The European Society for Parenteral and Enteral Nutrition (ESPEN) nutritional risk score was 1.35 ± 0.47 for Group I and 1.47 ± 0.58 for Group II (p = 0.62). With respect to severe morbidity there was no significant difference between Group III and Group IV: 2.01 ± 2.28 vs. 1.02 ± 3.67 (p = 0.54). Although there were minor differences, there were no major variations seen in the MNA or PINI scores comparing the four examined groups. No significant changes were observed in the biochemical parameters.
Conclusion. The study found no differences between post-operative morbidity or mortality and the pre-operative nutrition status of obese patients who underwent surgery due to esophageal cancer.

Key words

morbidity, mortality, nutrition, obesity, esophagectomy.

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