Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 2.1 (5-Year IF – 2.0)
Journal Citation Indicator (JCI) (2023) – 0.4
Scopus CiteScore – 3.7 (CiteScore Tracker 3.8)
Index Copernicus  – 171.00; MNiSW – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2014, vol. 23, nr 1, January-February, p. 85–89

Publication type: original article

Language: English

Characteristics of Focal Liver Lesions in Arterial Phase on Contrast-enhanced Ultrasound and Contrast- -enhanced Computed Tomography – Comparative Study

Xing-Hua Wang1,A,B,C,D,E,F, Ying Shi1,B, Huan-Hu Zhang2,B, Xia Ma1,B,C,D

1 Department of Ultrasound, the 2nd Clinical College of Shanxi Medical University, Taiyuan, China

2 Department of Hepatology, the 2nd Clinical College of Shanxi Medical University, Taiyuan, China

Abstract

Background. . To compare the features of focal liver lesions in the arterial phase on contrast-enhanced ultrasonography (CEUS) and contrast-enhanced computed tomography (CECT).
Material and Methods. . A total of 38 lesions in 29 patients with focal liver lesions (FLL) were examined with CEUS and CECT. The characteristics of the enhancement were determined, especially in the early arterial phase (0~25 s). The enhancement of FLL in CEUS and CECT graded as follows: grade 0 – no enhancement; grade I – peripheral enhancement or spotty enhancement at the center; grade II – spoke-like, honeycomb-like or heterogeneous enhancement; grade II – entire enhancement.
Results. On CEUS, the arriving time within 25 s was found in 36 out of 38 lesions (94.73%) and the peak time within 25 s in 29 lesions (76.32%). The number of grade II–III FLL was 25 (65.79%) on CEUS, and 13 (34.21%) on CECT showing a significant difference (p < 0.05).
Conclusion. Compared with CECT, CEUS plays an important role in the diagnosis of FLL with enhancement in the early arterial phase (< 25 s).

Key words

ultrasonography, helical computed tomography, contrast, focal liver lesions.

References (15)

  1. Oudkerk M, Van Ooijen B, Mali SP, Tjiam SL, Schmitz PI, Wigers T: Liver metastases from colorectal carcinoma: detection with continuous CT angiography. Radiology 1992, 185, 157–161.
  2. Takayasu K, Muramatsu Y, Furukawa H, Wakao F, Moriyama N, Takayama T, Yamasaki S, Sakamoto M, Hirohashi S: Early hepatocellular carcinoma: appearance at CT during arterial portography and CT arteriography with pathologic correlation. Radiology 1995, 194, 101–105.
  3. Seltzer SE, Getty DJ, Pickett RM, Swets JA, Sica G, Brown J, Saini S, Mattrey RF, Harmon B, Francis IR, Chezmar J, Schnall MO, Siegelman ES, Ballerini R, Bhat S: Multimodality diagnosis of liver tumors: feature analysis with CT, liver-specific and contrast-enhanced MR, and a computer model. Acad Radiol 2002, 9, 256–269.
  4. Lencioni R: European federation of societies for ultrasound in medicine and biology (EFSUMB) guidelines for the use of contrast agents in liver ultrasound: what is the impact in clinical practice? Eur Radiol 2005, Suppl 5, E98–103.
  5. Salvatore V, Borghi A, Piscaglia F: Contrast-enhanced ultrasound for liver imaging: recent advances. Curr Pharm Des 2012, 18, 2236–2252.
  6. Quaia E: Solid focal liver lesions indeterminate by contrast-enhanced CT or MR imaging: the added diagnostic value of contrast-enhanced ultrasound. Abdom Imaging 2012, 37, 580–590.
  7. Martie A, Sporea I, Popescu A, Sirli R, Dănilă M, Serban C, Ardelean M, Bota S, Sendroiu M, Chisevescu D: Contrast enhanced ultrasound for the characterization of hepatocellular carcinoma. Med Ultrason 2011, 13, 108– 113.
  8. Sirli R, Sporea I, Popescu A, Dănilă M, Martie A, Bota S, Jurchis A, Sendroiu M: Contrast enhanced ultrasound for the diagnosis of liver hemangiomas in clinical practice. Med Ultrason 2011, 13, 95–101.
  9. Quaia E: The real capabilities of contrast-enhanced ultrasound in the characterization of solid focal liver lesions. Eur Radiol 2011, 21, 457–462.
  10. Dietrich CF, Kratzer W, Strobe D, Danse E, Fessl R, Bunk A, Vossas U, Hauenstein K, Koch W, Blank W, Oudkerk M, Hahn D, Greis C: Assessment of metastatic liver disease in patients with primary extrahepatic tumors by contrast-enhanced sonography versus CT and MRI. World J Gastroenterol 2006, 12, 1699–1705.
  11. Gaiani S, Celli N, Piscaglia F, Cecilioni L, Losinno F, Giangregorio F, Mancini M, Pini P, Fornari F, Bolondi L: Usefulness of contrast-enhanced perfusional sonography in the assessment of hepatocellular carcinoma hypervascular at spiral computed tomography. J Hepatol 2004, 41, 421–426.
  12. Burns PN, Wilson SR: Focal liver masses: enhancement patterns on contrast-enhanced images-concordance of US scans with CT scans and MR images. Radiology 2007, 242, 162–174.
  13. Trillaud H, Bruel JM, Valette PJ, Vilgrain V, Schmutz G, Oyen R, Jakubowski W, Danes J, Valek V, Greis C: Characterization of focal liver lesions with SonoVue-enhanced sonography: international nulticenter-study in comparison to CT and MRI. World J Gastroenterol 2009, 15, 3748–3756.
  14. Giorgio A, Ferraioli G, Tarantino L, de Stefano G, Scala V, Scarano F, Coppola C, Del Viscovo L: Contrast-enhanced sonographic appearance of hepatocellular carcinoma in patients with cirrhosis: comparison with contrast-enhanced helical CT appearance. AJR Am J Roentgenol 2004, 183, 1319–1326.
  15. Maruyama H, Takahashi M, Ishibashi H, Yoshikawa M, Yokosuka O: Contrast-enhanced ultrasound for characterisation of hepatic lesions appearing nonhypervascular on CT in chronic liver diseases. Br J Radiol 2012, 85, 351–357.
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