Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
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ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
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Advances in Clinical and Experimental Medicine

2013, vol. 22, nr 6, November-December, p. 831–837

Publication type: original article

Language: English

Using Spectralis and Stratus Optical Coherence Tomography Devices to Analyze the Retinal Nerve Fiber Layer in Patients with Open-Angle Glaucoma – Preliminary Report

Analiza grubości warstwy włókien nerwowych siatkówki u pacjentów z jaskrą otwartego kąta za pomocą Spektralnego OCT i OCT Stratus – doniesienie wstępne

Małgorzata Mulak1,A,D,E, Anna Cicha2,B,C,D, Kamil Kaczorowski1,D,E,G, Bartłomiej Markuszewski1,D,G,, Marta Misiuk-Hojło1,F

1 Department and Clinic Ophthalmology, Wroclaw Medical University, Poland

2 Department of Basic Technical Problems, Wroclaw University of Technology, Poland

Abstract

Background. During the study at the Ophthalmology Clinic of Wroclaw Medical University retinal nerve fiber layer (RNFL) thickness was examined in 35 patients with open-angle glaucoma.
Objectives. The aim of the study was to analyse RNFL thickness measurements by 2 different optical coherence tomography (OCT) devices.
Material and Methods. The study group consisted of 35 patients with open-angle glaucoma (aged 48–76 years, including 20 women and 15 men – 70 eyes) with intraocular pressure below 19 mm Hg, treated pharmacologically. The subjects were examined using a Stratus Time Domain OCT (TD-OCT), produced by Zeiss, and a Spectralis Spectral Domain OCT (SD-OCT), manufactured by Heidelberg Engineering. The OCT examination was carried out with both devices on the same day in random order.
Results. The study shows that the results obtained using the 2 devices are correlated, although the average measurements of RNFL thickness were lower for the Spectralis OCT in comparison with those taken by the Stratus OCT. The strongest correlation was found for the temporal and nasal quadrants.
Conclusion. The study results using the Spectralis OCT and Stratus OCT are similar, but not identical, so followup tests should be performed on the same apparatus as in the initial testing. Considering the new generation of apparatus and the more precise measurement algorithm, the results obtained using the Spectralis SD-OCT seem more accurate

Streszczenie

Wprowadzenie.. W Klinice Okulistyki Uniwersytetu Medycznego we Wrocławiu zbadano 35 pacjentów z jaskrą otwartego kąta pod kątem grubości warstwy włókien nerwowych siatkówki (RNFL).
Cel pracy. . Analiza grubości RNFL mierzonych za pomocą 2 urządzeń OCT.
Materiał i metody. . Zbadano 35 pacjentów z jaskrą otwartego kąta w wieku 48–76 lat (w tym 20 kobiet, 15 mężczyzn) za pomocą TD-OCT Stratus firmy Zeiss oraz SD-OCT Spektralnego firmy Heidelberg Engineering. Wykonano badania OCT obydwoma aparatami, tego samego dnia, w kolejności losowej.
Wyniki.  Wyniki badań wskazują, że rezultaty uzyskane za pomocą 2 aparatów są ze sobą skorelowane, jednak średnie grubości RNFL były mniejsze w przypadku Spektralnego OCT w porównaniu z OCT Stratus.
Wnioski. . Wyniki badań z użyciem Spectralnego OCT i OCT Stratus są podobne, ale nie identyczne, dlatego badania kontrolne powinny być wykonywane na tych samych aparatach

Key words

glaucoma, RNFL (retinal nerve fiber layer), Spectralis OCT, Stratus OCT.

Słowa kluczowe

jaskra, RNFL (retinal nerve fiber layer – warstwa włókien nerwowych siatkówki), Spectralne OCT, Stratus OCT.

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