Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 1.736
5-Year Impact Factor – 2.135
Index Copernicus  – 168.52
MEiN – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2010, vol. 19, nr 6, November-December, p. 723–730

Publication type: original article

Language: English

Risk Factors for Large Intestine Cancer in Clinical Material

Czynniki ryzyka nowotworów jelita grubego w materiale klinicznym

Hady R. Hady1,, Fabian A. Kamiński1,, Maria Sołdatow1,, Magdalena E. Łuba1,, Jadwiga Snarska1,, Jerzy R. Ładny1,, Jacek W. Dadan1,

1 University Hospital in Bialystok, 1st Department of General and Endocrinological Surgery, Białystok, Poland

Abstract

Background. Large intestine cancers are a huge prognostic, diagnostic and therapeutic problem, both in highly developed and developing countries, and their pathogenesis still remains unexplained. Many epidemiological and environmental factors are responsible for the inception and development of cancer of the large intestine. Objectives,
Material and Methods. The aim of the work was to present the cases of large bowel cancer from among 14,543 patients hospitalized in the 1st Department of General and Endocrinological Surgery of the Medical University of Bialystok, Poland, from 1999 to 2008, and to identify the risk factors for large bowel cancer.
Results. Between 1999 and 2008, 14,543 patients aged from 17 to 92 years old were hospitalized in this Department. This group included 704 patients (4.8%) with bowel tumors. Precancerous conditions including polyps and nonspecific bowel inflammations were observed in 498 patients (3.4% of the whole group).
Conclusion. Large intestinal tumors frequently coexist with various environmental factors, such as the place of residence, diet and level of physical activity, and with epidemiological factors. Benign tumors and non-specific large intestine inflammations are currently the most important precancerous lesions.

Streszczenie

Wprowadzenie. Nowotwory jelita grubego pozostają dużym problemem prognostycznym, diagnostycznym i leczniczym w naszych czasach, zarówno w krajach wysoko, jak i nisko cywilizowanych, a ich patogeneza w dalszym ciągu pozostaje nie do końca wyjaśniona. Za powstanie i rozwój raka jelita grubego jest odpowiedzialnych wiele czynników epidemiologicznych i środowiskowych. Cel pracy, materiał i metody. Przedstawienie czynników ryzyka nowotworów jelita grubego w materiale klinicznym.
Wyniki. W latach 1999–2008 w I Klinice Chirurgii Ogólnej i Endokrynologicznej Uniwersytetu Medycznego w Białymstoku hospitalizowano 14543 pacjentów. W tej grupie znalazło się 704 (4,8%) chorych z nowotworami jelita grubego. Stany przedrakowe, do których zalicza się polipy i nieswoiste zapalenia jelita grubego zaobserwowano u 498 pacjentów, tj. 3,4% ogółu.
Wnioski. Nowotwory jelita grubego pozostają istotnym problemem diagnostycznym i leczniczym. Często współwystępują z różnymi czynnikami środowiskowymi, takimi jak miejsce zamieszkania, dieta, stopień aktywności fizycznej, oraz czynnikami epidemiologicznymi. Nowotwory łagodne oraz nieswoiste zapalenia jelita grubego pozostają obecnie najistotniejszymi stanami przedrakowymi.

Key words

large intestine cancer, epidemiology, risk factors

Słowa kluczowe

nowotwory jelita grubego, epidemiologia, czynniki ryzyka

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