Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 1.727
Index Copernicus  – 166.39
MEiN – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2006, vol. 15, nr 6, November-December, p. 1093–1098

Publication type: review article

Language: English

Reproductive Disorders and Celiac Disease

Zaburzenia rozrodczości u chorych na celiakię

Ewa Waszczuk1,, Wojciech Homola1,

1 Chair and Department of Gastroenterology and Hepatology, Silesian Piasts University of Medicine, Wrocław, Poland

Abstract

Celiac disease is the most common disease, that is conditioned genetically. It occurs at approximately 1% of the population. The changes in nutrition of infants, that were introduced by pediatricians, retarded the disclosure of the disease in childhood. It is diagnosed mostly in the age of 18 to 60. Although the main cause of the disease is a harm to mucous membrane of the small intestine by the peptides in proteins of some cereal, celiakia is a multisystemic disease, which can be followed by other disorders or injuries of, different from intestine, organs or systems, among the others: cardiovascular, nervous, motion and others. It happens very rarely, that the disease proceeds only excluding the intestines. On the basis of the references, the survey on the influence of celiakia to reproduction was made. As it comes from the other research, this influence is stronger at women than at men.

Streszczenie

Choroba trzewna (celiakia) jest najczęstszym schorzeniem uwarunkowanym genetycznie, które występuje u około 1% populacji. Zmiany żywienia niemowląt wprowadzone przez pediatrów spowodowały rzadsze ujawnianie się choroby w dzieciństwie. Najczęściej jest rozpoznawana u dorosłych ludzi między 18 a 60 r.ż. Chociaż istotą choroby jest uszkodzenie błony śluzowej jelita cienkiego przez peptydy zawarte w białkach niektórych zbóż, celiakia jest chorobą ogólnoustrojową, której mogą towarzyszyć inne choroby lub uszkodzenia innych niż jelito narządów lub układów, m.in. układu krążenia, nerwowego, ruchu, itd. Rzadko się zdarza, żeby choroba przybierała postać wyłącznie pozajelitową. Dokonano przeglądu piśmiennictwa na temat wpływu choroby trzewnej na funkcje rozrodcze. Jak wynika z badań, wpływ ten jest silniejszy u kobiet niż u mężczyzn.

Key words

celiakia, extraintestinal symptoms, reproduction

Słowa kluczowe

choroba trzewna, objawy pozajelitowe, rozrodczość

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