Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 1.727
Index Copernicus  – 166.39
MEiN – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly

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Advances in Clinical and Experimental Medicine

2006, vol. 15, nr 6, November-December, p. 1063–1071

Publication type: review article

Language: English

Effect of Vitamin E on the Physical Work Capacity

Oddziaływanie witaminy E na obciążenie fizyczne

Yousif Saleh1,, Wojciech Wójcik2,, Andrzej Karmowski3,, Abdo Katib4,, Mikołaj Karmowski3,, Maciej Siewiński2,

1 Department of Technical Molecular, Silesian Piasts University of Medicine in Wrocław, Poland

2 Faculty of Public Healthy, Silesian Piasts University of Medicine in Wrocław, Poland

3 1st Clinic of Obstetrics and Gynecology, Silesian Piasts University of Medicine in Wrocław, Poland

4 II Department of Surgery and Oncology, Silesian Piasts University of Medicine in Wrocław, Poland


It has been widely noted that vitamin E shows numerous beneficial effects through its antioxidant properties and beyond; consequently, vitamin E is expected to prevent degenerative diseases. In the field of sports medicine, many studies dealing with vitamin E have been conducted, originally from the point of view of its effects on physical performance. Although some earlier studies indicated that vitamin E supplementation could improve physical performance, defects in the study design or statistical analysis were pointed out at a later time. The majority of subsequent, well−controlled studies have reported no significant effect on physical performance from vitamin E supplementation. In conclusion, the authors suggest that endurance exercise may promote free radical generation in the body, and vitamin E may play an important role in preventing the free radical and DNA damage associated with endurance exercise. There is also evidence of free radical involvement in exercise−induced muscle injury. Vitamin E supplementation might be expected to prevent muscle and DNA damage caused by exercise in humans.


Dotychczas zostały dokładnie opracowane informacje dotyczące działania witaminy E, które potwierdzają, że nie tylko jej właściwości antyutleniające, ale również inne mogą zapobiegać pojawianiu chorób związanych ze zmianami zwyrodnieniowymi. W badaniach dotyczących medycyny wysiłku fizycznego podkreślono wpływ witaminy E na działania, które wysiłkowi towarzyszą. Potwierdza się, że podawanie witaminy E w formie suplementów polepsza zdolność organizmu do wysiłku fizycznego, co dokładnie wyjaśniono na podstawie dalszych badań, w tym analizy statystycznej. Wiele z nich potwierdziło pozytywny wpływ działania witaminy E na zmiany spowodowane obciążeniem fizycznym. Sugerują, że pełni funkcję ochronną w organizmie, w tym również, że może ograniczać uwalnianie się wolnych rodników po wysiłku fizycznym. Wolne rodniki uwalniane pod wpływem obciążenia fizycznego mogą uszkodzić DNA, a nawet mięśnie. Witamina E podawana w formie suplementów powinna zapobiegać patogennym zmianom w mięśniach osób wykonujących wysiłek fizyczny, które mogą powstawać na skutek uszkodzenia DNA.

Key words

vitamin E, free radical, physical exercise

Słowa kluczowe

witamina E, wolne rodniki, wysiłek fizyczny

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