Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
5-Year IF – 2.0, IF – 1.9, JCI (2024) – 0.43
Scopus CiteScore – 4.3
Q1 in SJR 2024, SJR score – 0.598, H-index: 49 (SJR)
ICV – 161.00; MNiSW – 70 pts
Initial editorial assessment and first decision within 24 h

ISSN 1899–5276 (print), ISSN 2451-2680 (online)
Periodicity – monthly

Download original text (EN)

Advances in Clinical and Experimental Medicine

2019, vol. 28, nr 7, July, p. 871–878

doi: 10.17219/acem/94070

Publication type: original article

Language: English

Download citation:

  • BIBTEX (JabRef, Mendeley)
  • RIS (Papers, Reference Manager, RefWorks, Zotero)

Life activity, disease acceptance and quality of life in patients treated with renal replacement therapy since childhood

Dominika Adamczuk1,A,B,C,D, Maria Roszkowska-Blaim1,A,C,D,E, Beata Leszczyńska1,A,B,D,E, Małgorzata Pańczyk-Tomaszewska1,A,D,E,F

1 Department of Pediatrics and Nephrology, Medical University of Warsaw, Poland

Abstract

Background. Advances in the treatment of chronic kidney disease (CKD) resulted in expanding therapy goals from simple prolongation of life to a return to normal social functioning and having an active and satisfactory life after reaching adulthood.
Objectives. The aim of the study was to evaluate life activity, disease acceptance (DA) and quality of life (QOL) in patients with end-stage renal disease (ESRD) treated with renal replacement therapy (RRT) since childhood.
Material and Methods. We surveyed 117 patients aged .16 years on RRT since childhood. The control group included 25 healthy subjects. We used questionnaires that included a sociodemographic questionnaire (questions regarding education, work, family, and offspring), Acceptance of Illness Scale (AIS), Satisfaction With Life Scale, and Kidney Disease Quality of Life (KDQOL).
Results. A completed survey was returned by 45 respondents aged 27.16 }6.78 years, among whom 82.2% had a transplanted kidney and 17.8% were on hemodialysis (HD). Higher education was reported by 18.18% of respondents, secondary and primary by 63.64% and 18.18%, respectively. Employment was reported by 46.67% of the respondents. A family was started by 35% of women and 4% of men. Good DA was found in 28.9% of the respondents. Satisfaction with life was lower in the study group compared to the control group. We found statistically significant correlations between the age when the kidney disease was diagnosed and satisfaction with life (r = 0.33), and between the time since the last change of RRT modality and emotional well-being (r = 0.34). The number of kidney transplantations correlated negatively with emotional component of QOL (r = .0.66) and emotional well-being (r = .0.73).
Conclusion. Patients treated with RRT were quite well adapted to their chronic disease but showed less ability to live independently. Young age at the diagnosis of kidney disease, loss of kidney transplant and living on social security benefit had a negative effect on their emotional well-being.

Key words

quality of life, dialysis, end stage renal disease, kidney transplant, childhood

References (29)

  1. Heijmans M, Rijken M, Foets M, de Ridder D, Schreurs K, Bensingt J. The stress of being chronically ill: From disease-specific to task-specific aspects. J Behav Med. 2004;27(3):255–271.
  2. Kalantar-Zadeh K, Kopple JD, Block G, Block G, Humphreys MH. Association among SF-36 quality of life measures and nutrition, hospitalization and mortality in hemodialysis. J Am Soc Nephrol. 2001;12(12):2797–2806.
  3. Mapes DL, Lopes AA, Satayathum S, et al. Health-related quality of life as a predictor of mortality and hospitalization: The Dialysis Outcomes and Practice Patterns Study (DOPPS). Kidney Int. 2003;64(1):339–349.
  4. Bocheńska M, Bednorz R, Niezbrzycka-Andrzejewska K, Wikiera I, Morawska Z. Psychological aspects of the treatment of children with terminal renal failure by repeated hemodialysis [in Polish]. Wiad Lek. 1992;45(1–2):28–31.
  5. Rosenkranz J, Reichwald-Klugger E, Oh J, Turzer M, Mehls O, Schaefer F. Psychosocial rehabilitation and satisfaction with life in adults with childhood onset of end-stage renal disease. Pediatr Nephrol. 2005;20(9):1288–1294.
  6. Groothoff JW, Groothenhuis MA, Offringa M, Stronks K, Hutten GJ, Heymans HS. Social consequences in adult life of end-stage renal disease in childhood. J Pediatr. 2005;146(4):512–517.
  7. Juczyński Z. Narzędzia pomiaru w promocji i psychologii zdrowia. Pracownia Testów Psychologicznych Polskiego Towarzystwa Psychologicznego, Warsaw 2001. [in Polish]
  8. Hays RD, Kallich JD, Mapes DL, Coons SJ, Amin N, Carter WB. Kidney Disease Quality of Life Short Form (KDQOL-SFTM), Version 1.2. A Manual for Use and Scoring. Rand Santa Monica. CA, University of Arizona 1995 p. 7928
  9. Rocznik Demograficzny Polski 2010, Zakład Wydawnictw Statystycznych, Główny Urząd Statystyczny, Warszawa 2010 p.162–163. https://stat.gov.pl/obszary-tematyczne/roczniki-statystyczne/roczniki-statystyczne/rocznik-demograficzny-2010,3,4.htm
  10. Bulla M, Rosenkranz J. 25 years kidney replacement therapy in childhood and adolescence success of somatic and psychosocial rehabilitation [in German]. Versicherungsmedizin. 1996;48(3):85–89.
  11. Potter DE, Najarian J, Belzer F, et al. Long-term results of renal transplantation in children. Kidney Int. 1991;40:752–756.
  12. Bartosh SM, Leverson G, Robillard D, Sollinger HW. Long-term outcomes in pediatric renal transplant recipients who survive into adulthood. Transplantation. 2003;76(8):1195–2000.
  13. Rizzoni G, Ehrich JHH, Broyer M, et al. Rehabilitation of young adults during renal replacement therapy in Europe. 2. Schooling, employment and social situation. Nephrol Dial Transplant. 1992;7(7):579–586.
  14. Kärrfelt HME, Berg UB. Long-term psychosocial outcome after renal transplantation during childhood. Pediatr Transplant. 2008;12(5):557–562.
  15. Keogh AM, Feehally J. A quantitative study comparing adjustment and acceptance of illness in adults on renal replacement therapy. ANNA J. 1999;26(5):471–417.
  16. Wlazło A, Kleszczyński J, Makulska I, et al. Psychological factors versus the choice of a renal replacement therapy for patients with chronic renal insufficiency. Nephrol Dial Pol. 2008;12:221–225.
  17. Lopes AA, Bragg-Gresham JL, Goodkin DA, et al. Factors associated with health-related quality of life among hemodialysis patients in DOPPS. Qual Life Res. 2007;16(4):545–555.
  18. Groothoff JW, Grootenhuis M, Offringa M, et al. Quality of life in adults with end-stage renal disease since childhood is only partially impaired. Nephrol Dial Transplant. 2003;18:310–317.
  19. Lanreneau K, Lee K, Landreneau MD. Quality of life in patients undergoing hemodialysis and renal transplantation: A meta-analytic study. Nephrol Nurs J. 2010;37(1):37–34.
  20. Muehrer RJ, Becker BN. Life after transplantation. New transitions in quality of life and psychological distress. Semin Dial. 2005;18(2):124–131.
  21. Bakewell AB, Higgins RM, Edmunds ME. Quality of life in peritoneal dialysis patients: A decline over time and association with clinical outcomes. Kidney Int. 2002;61(1):239–248.
  22. Baiardi F, Degli Esposti E, Cocchi R, et al. Effects of clinical and individual variables on quality of life in chronic renal failure patients. J Nephrol. 2002;15(1):61–67.
  23. Kostro JZ, Hellmann A, Kobiela J, et al. Quality of life after kidney transplantation: A prospective study. Transplant Proc. 2016;48(1):50–54.
  24. Mielck A. Vogelmann M, Leidl R. Health related quality of life and socioeconomic status: Inequalities among adults with a chronic disease. Health Qual Life Outcomes. 2014;12:58–67.
  25. Gentile S, Beauger D, Speyer E, et al. Factors associated with health-related quality of life in renal transplant recipients: Results of a national survey in France. Health Qual Life Outcomes. 2013;11:88–100.
  26. Niedzielski A, Humeniuk E, Błaziak P, Fedoruk D. The level of approval in selected chronic diseases [in Polish]. Wiad Lek. 2007;60(5–6):224–227.
  27. Zagozdzon P, Kolarzyk E, Marcinkowski JT. Quality of life and rural place of residence in Polish women: Population-based study. Ann Agricult Env Med. 2011;18(2):429–432.
  28. Rutkowski B, Nowaczyk R, Mierzicki P, et al. Quality of care vs quality of life in hemodialysis centers in Poland in the year 2005. Part III. Quality of life [in Polish]. Nephrol Dial Pol. 2008;12:149–155.
  29. Griva K, Stygall J, Ng JH, Davenport A, Harrison MJ, Newman S. Prospective changes in health-related quality of life and emotional outcomes in kidney transplantation over 6 years. J Transplant. 2011;2011:671571.
© Wroclaw Medical University