Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
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Advances in Clinical and Experimental Medicine

2018, vol. 27, nr 9, September, p. 1285–1293

doi: 10.17219/acem/73699

Publication type: original article

Language: English

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Extremely low frequency electromagnetic field reduces oxidative stress during the rehabilitation of post-acute stroke patients

Natalia Cichoń1,A,B,C,D,F, Paulina Rzeźnicka1,B, Michał Bijak1,A,C,D,F, Elżbieta Miller2,3,A,D,E,F, Sergiusz Miller4,E,F, Joanna Saluk1,A,C,D,E,F

1 Department of General Biochemistry, University of Lodz, Poland

2 Department of Physical Medicine, Medical University of Lodz, Poland

3 Neurorehabilitation Ward, III General Hospital in Lodz, Poland

4 Department of Orthodontics, Medical University of Lodz, Poland

Abstract

Background. One of the therapeutic methods used in stroke rehabilitation is magnetotherapy using extremely low frequency and variable pulse shape electromagnetic field (ELF-EMF).
Objectives. The aim of our study was to investigate the effect of magnetotherapy on the condition of postacute stroke patients, as measured by plasma oxidative stress markers and clinical parameters which show the progress of rehabilitation.
Material and Methods. The selected 57 post-stroke patients were divided into 2 groups, those with ELFEMF therapy and those without. The level of oxidative stress in the plasma was estimated by typical markers: thiobarbituric acid reactive substances (TBARS), thiol groups, and carbonyl groups. The effect of ELF-EMF on the course of the patients’ rehabilitation following ischemic stroke was evaluated with the use of scales of physical activity and mental state: Activities of Daily Living (ADL), Mini-Mental State Examination (MMSE) and Geriatric Depression Scale (GDS).
Results. Our comparative analysis showed that all parameters of oxidative stress are significantly reduced during rehabilitation using ELF-EMF, compared to the control group rehabilitated only by kinesiotherapy. We also recorded much higher therapeutic benefits using magnetotherapy, which revealed a significant improvement of clinimetric parameters.
Conclusion. The ELF-EMF therapy meaningfully improves the overall condition of patients through a decrease of oxidative stress markers and it significantly affects the psychophysical abilities of patients after stroke. The change in carbonyl group level correlates with the change in the degree of physical and mental disability; therefore, it could be a marker for the effectiveness of rehabilitation.

Key words

stroke, rehabilitation, oxidative stress, extremely low frequency electromagnetic field therapy

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