Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
5-Year IF – 2.0, IF – 1.9, JCI (2024) – 0.43
Scopus CiteScore – 4.3
Q1 in SJR 2024, SJR score – 0.598, H-index: 49 (SJR)
ICV – 161.00; MNiSW – 70 pts
Initial editorial assessment and first decision within 24 h

ISSN 1899–5276 (print), ISSN 2451-2680 (online)
Periodicity – monthly

Download original text (EN)

Advances in Clinical and Experimental Medicine

2017, vol. 26, nr 9, December, p. 1411–1418

doi: 10.17219/acem/68900

Publication type: original article

Language: English

Download citation:

  • BIBTEX (JabRef, Mendeley)
  • RIS (Papers, Reference Manager, RefWorks, Zotero)

Knowledge and selected variables as determinants of the quality of life and general health of patients with rheumatoid arthritis

Aleksandra Pytel1,2,A,B,C,D,E,F, Iwona Demczyszak1,B,C,E, Edyta Sutkowska1,C,E,F, Joanna Rosińczuk2,E,F, Izabela Kuberka2,B,C,E, Aleksandra Kołtuniuk2,B,C,D,E

1 Department of Medical Rehabilitation, Wroclaw Medical University, Poland

2 Department of Nervous System, Wroclaw Medical University, Poland

Abstract

Background. Rheumatoid arthritis (RA) is an incurable disease resulting in progressive disability, which is associated with the loss of productivity and the inability to earn money, which might lead to a financial burden on the patient’s family. Undoubtedly, the clinical picture of the disease and its consequences lead to the reduction of the quality of life.
Objectives. The aim of this study is to evaluate the influence of selected factors on the subjective assessment of the quality of life and general health of patients with RA.
Material and Methods. The study was conducted among 270 patients with RA treated at the Department of Rheumatology and Internal Medicine. The quality of life and general health were assessed with the use of the SF-36 and the GHQ-30 questionnaires.
Results. In the study group, a statistically significant correlation between the results of the SF-36 and the GHQ-30 questionnaires was observed. It has been shown that the level of role limitations due to physical health problems (RP) is mostly affected by interpersonal relationships based on GHQ-30 questionnaire (p = 0.002), general health (GHQ-30) (p = 0.001) and subjective health condition (SF-36) (p < 0.001). In contrast, general health (GHQ-30) is positively affected by education (p = 0.003) and professional activity (p = 0.001), and negatively affected by a positive family history of RA (p = 0.002), frequent hospitalization (p = 0.008) and poor subjective health condition (p < 0.001).
Conclusion. People with poor subjective health condition are characterized by more limited activity due to physical health and lower general health condition. General health (GHQ-30) in patients with rheumatoid arthritis is influenced by education, place of residence, professional work, family history of RA and subjective health status.

Key words

quality of life, rheumatoid arthritis (RA), SF-36 questionnaire, General Health Questionnaire (GHQ)

References (35)

  1. Benucci M, Rogai V, Atzeni F, Hammen V, Sarzti-Puttini P, Migliore A. Costs associated with rheumatoid arthritis in Italy: Past, present, and future. Clin Outcomes Res CEOR. 2016;8:33–41.
  2. Talotta R, Berzi A, Atzeni F, et al. Paradoxical expansion of Th1 and Th17 lymphocytes in rheumatoid arthritis following infliximab treatment: A possible explanation for a lack of clinical response. J Clin Immunol. 2015;35:550–557.
  3. Colebatch-Bourn AN, Edwards CJ, Collado P, et al. EULAR-PReS points to consider for the use of imaging in the diagnosis and management of juvenile idiopathic arthritis in clinical practice. Ann Rheum Dis. 2015;74:1946–1957.
  4. Peng J, Gong Y, Zhang Y, Xiao Z, Zeng Q, Chen S. Bone mineral density in patients with rheumatoid arthritis and 4-year follow-up results. J Clin Rheumatol Pract Rep Rheum Musculoskelet Dis. 2016;22:71–74.
  5. van der Woude D, Toes REM, Scherer HU. How undifferentiated arthritis evolves into chronic arthritis. Best Pract Res Clin Rheumatol. 2014;28:551–564.
  6. Tsai CL, Lin CF, Lin HT, et al. How kinematic disturbance in the deformed rheumatoid thumb impacts on hand function: A biomechanical and functional perspective. Disabil Rehabil. 2016;1–8.
  7. Moreira E, Jones A, Oliveira HA, Jennings F, Fernandes A, Natour J. Effectiveness of insole use in rheumatoid feet: A randomized controlled trial. Scand J Rheumatol. 2016;1–8.
  8. Larsson I, Fridlund B, Arvidsson B, Teleman A, Svedberg P, Bergman S. A nurse-led rheumatology clinic versus rheumatologist-led clinic in monitoring of patients with chronic inflammatory arthritis undergoing biological therapy: A cost comparison study in a randomised controlled trial. BMC Musculoskelet Disord. 2015;16:354.
  9. Uutela T, Kautiainen H, Järvenpää S, Hakala M, Häkkinen A. Self-rated health in patients with rheumatoid arthritis is associated with health-related quality of life but not with clinical variables. Scand J Rheumatol. 2016;45:288–293.
  10. Nüßlein HG, Alten R, Galeazzi M, et al. Efficacy and prognostic factors of treatment retention with intravenous abatacept for rheumatoid arthritis: 24-month results from an international, prospective, real-world study. Clin Exp Rheumatol. 2016;34:489–499.
  11. Jennings F, Toffolo S, de Assis MR, Natour J. Brazil Patient Knowledge Questionnaire (PKQ) and evaluation of disease-specific knowledge in patients with rheumatoid arthritis. Clin Exp Rheumatol. 2006;24:521–528.
  12. Nawata M, Saito K, Fukuyo S, Hirata S, Tanaka Y. Clinically relevant radiographic progression in joint destruction in RA patients with abnormal MMP-3 or high levels of CRP despite 1-year treatment with infliximab. Mod Rheumatol Jpn Rheum Assoc. 2016;26:807–812.
  13. Sparks JA, Chang SC, Deane KD, et al. Associations of smoking and age with inflammatory joint signs among first-degree relatives without rheumatoid arthritis: Results from the studies of the etiology of RA. Arthritis Rheumatol. 2016;68:1828–1838.
  14. Pytel A, Wrzosek Z. Estimation of patient knowledge on rheumatoid arthritis in the range of their own disease-preliminary study. Adv Clin Exp Med Off Organ Wroclaw Med Univ. 2012;21:343–351.
  15. McHorney CA, Ware JE, Raczek AE. The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care. 1993;31:247–263.
  16. Frydecka D, Małyszczak K, Chachaj A, Kiejna A. Struktura czynnikowa Kwestionariusza Ogólnego Zdrowia (GHQ-30). Psychiatr Pol. 2010;44:341–351.
  17. Abu Al-Fadl EM, Ismail MA, Thabit M, El-Serogy Y. Assessment of health-related quality of life, anxiety and depression in patients with early rheumatoid arthritis. Egypt Rheumatol. 2014;36:51–56.
  18. West E, Jonsson SW. Health-related quality of life in rheumatoid arthritis in Northern Sweden: A comparison between patients with early RA, patients with medium-term disease and controls, using SF-36. Clin Rheumatol. 2005;24:117–122.
  19. Azevedo AF, Petribú KC, Lima Mde N, et al. Quality of life of patients with rheumatoid arthritis under biological therapy. Rev Assoc Médica Bras. 2015;61:126–131.
  20. Baloglu HH, Askin A, Yener M. Determination of the factors that affect health-related quality of life in patients with rheumatoid arthritis. Acta Medica Mediterr. 2015;31:687–695.
  21. Gong G, Mao J. Health-related quality of life among Chinese patients with rheumatoid arthritis: The predictive roles of fatigue, functional disability, self-efficacy, and social support. Nurs Res. 2016;65:55–67.
  22. Jankowska-Polańska B, Nawrocka A, Uchmanowicz I, Rosińczuk J, Polański J. Quality of life and methods of coping with stress depending on the used form of therapy of rheumatoid arthritis treatment. Prog Health Sci. 2014;4:102–110.
  23. Matcham F, Scott IC, Rayner L, et al. The impact of rheumatoid arthritis on quality-of-life assessed using the SF-36: A systematic review and meta-analysis. Semin Arthritis Rheum. 2014;44:123–130.
  24. Wysocka-Skurska I, Sierakowska M, Kułak W. Evaluation of quality of life in chronic, progressing rheumatic diseases based on the example of osteoarthritis and rheumatoid arthritis. Clin Interv Aging. 2016;11:1741–1750.
  25. Jankowska B, Uchmanowicz I, Polański J, Uchmanowicz B. Czynniki kliniczne i socjodemograficzne determinujące jakość życia w reumatoidalnym zapaleniu stawów. Fam Med Prim Care Rev. 2010;12:1027–1034.
  26. van Vilsteren M, Boot CR, Knol DL, et al. Productivity at work and quality of life in patients with rheumatoid arthritis. BMC Musculoskelet Disord. 2015;16:107.
  27. Moćko J, Zurzycka P. Jakość życia pacjentów z reumatoidalnym zapaleniem stawów – doniesienia wstępne. Pielęgniarstwo XXI Wieku. 2013;1:15–19.
  28. Haroon N, Aggarwal A, Lawrence A, Agarwal V, Misra R. Impact of rheumatoid arthritis on quality of life. Mod Rheumatol Jpn Rheum Assoc. 2007;17:290–295.
  29. Wan SW, He HG, Mak A, et al. Health-related quality of life and its predictors among patients with rheumatoid arthritis. Appl Nurs Res. 2016;30:176–183.
  30. Sierakowska M, Matys A, Kasior A, et al. Ocena jakości życia pacjentów z reumatoidalnym zapaleniem stawów. Reumatologia. 2006;44:298–303.
  31. Wisłowska M, Kanecki K, Tyszko P, Kapała M. Jakość życia zależna od zdrowia u pacjentów z reumatoidalnym zapaleniem stawów. Reumatologia. 2010;48:104–111.
  32. Maiden NL. Quantifying the burden of emotional ill-health amongst patients referred to a specialist rheumatology service. Rheumatology. 2003;42:750–757.
  33. Mäkeläinen P, Vehviläinen-Julkunen K, Pietilä AM. Rheumatoid arthritis patients’ knowledge of the disease and its treatments: A descriptive study. Musculoskeletal Care. 2009;7:31–44.
  34. Ruszkowski J, Leśniowska J. Rzeczywiste, ekonomiczne koszty choroby w Polsce. Pol Stow Zarządznia Wiedzą Ser Stud Mater. 2010;25:244–256.
  35. Michaud K, Bombardier C, Emery P. Quality of life in patients with rheumatoid arthritis: Does abatacept make a difference? Clin Exp Rheumatol. 2007;25:S35–45.