Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
5-Year IF – 2.0, IF – 1.9, JCI (2024) – 0.43
Scopus CiteScore – 4.3
Q1 in SJR 2024, SJR score – 0.598, H-index: 49 (SJR)
ICV – 161.00; MNiSW – 70 pts
Initial editorial assessment and first decision within 24 h

ISSN 1899–5276 (print), ISSN 2451-2680 (online)
Periodicity – monthly

Download original text (EN)

Advances in Clinical and Experimental Medicine

2017, vol. 26, nr 8, November, p. 1207–1212

doi: 10.17219/acem/66992

Publication type: original article

Language: English

Download citation:

  • BIBTEX (JabRef, Mendeley)
  • RIS (Papers, Reference Manager, RefWorks, Zotero)

Implementation of mild therapeutic hypothermia for post-resuscitation care of sudden cardiac arrest survivors in cardiology units in Poland

Łukasz Kołtowski1,A,B,C,D,E,F, Karolina Malesa1,B,C,D,F, Mariusz Tomaniak1,A,C,E,F, Janina Stępińska2,A,C,E,F, Beata Średniawa3,A,C,E,F, Paulina Karolczyk1,A,B,C,F, Dominika Puchta1,A,B,C,F, Robert Kowalik1,A,C,D,F, Elżbieta Kremis2,A,B,C,E,F, Krzysztof J. Filipiak1,A,C,E,F, Marek Banaszewski2,A,B,E,F, Grzegorz Opolski1,A,C,E,F, Marta Bagińska1,D

1 1st Department of Cardiology, Medical University of Warsaw, Poland

2 Intensive Cardiac Care Clinic, Institute of Cardiology, Warszawa, Poland

3 Department of Cardiology, Congenital Heart Diseases and Electrotherapy, Medical University of Silesia, Silesian Center for Heart Diseases, Zabrze, Poland

Abstract

Background. The post-cardiac arrest (CA) period is often associated with secondary damage of the brain that leads to severe neurological deficits. The current practice guidelines recommend the use of therapeutic hypothermia (TH) to prevent neurological deficit and improve survival.
Objectives. The aim of the study was to investigate the implementation of medical guidelines in clinical practice and to evaluate the barriers for implementation of TH in cardiology units in Poland.
Material and Methods. A telephone survey, fax and online inquiry form were used to assess the implementation of TH in cardiology units in the management of unconscious patients after cardiac arrest (CA). The questions addressed the local practice, TH protocol, reasons for not using TH and outcomes of CA patients.
Results. We obtained information from 79 units out of 150 asked (53%). At the time of the survey, 24 units (30.8%) were using TH as part of their post-CA management. Of all CA patients, 45% underwent TH in cardiac intensive care units (CICU), 37.5% in the coronary care unit (CCU) and 12.5% in the intensive care unit (ICU). The major barrier for the implementation of TH declared by the non-cooling centers was lack of sufficient knowledge regarding the technique and protocol, as well as experience (37%); access to dedicated equipment was not perceived as an obstacle.
Conclusion. The number of cardiology units that provide TH for comatose CA patients is low. The main limiting factor for wider use of TH is lack of knowledge and experience. There is a clear need for urgent educational activities for cardiology units. The benefits of TH still have not reached their potential in cardiology units.

Key words

cardiac arrest, therapeutic hypothermia, resuscitation, hypothermia registry, target temperature management

References (17)

  1. Skrifvars MB, Varghese B, Parr MJ. Survival and outcome prediction using the Apache III and the out-of-hospital cardiac arrest (OHCA) score in patients treated in the intensive care unit (ICU) following out-of-hospital, in-hospital or ICU cardiac arrest. Resuscitation.2012;83:728–733.
  2. Belliard G, Catez E, Charron C, et al. Efficacy of therapeutic hypothermia after out-of-hospital cardiac arrest due to ventricular fibrillation. Resuscitation. 2007;75:252–259.
  3. Bernard S, Gray T, Buist M, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002;346:557–563.
  4. Hypothermia after Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med. 2002;346:549–556.
  5. Steg PG, James SK, Atar D, et al. ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The task force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC). Eur Heart J. 2012;33:2569–2619.
  6. Nolan JP, Soar J, Cariou A, et al. European Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015: Section 5 of the European Resuscitation Council Guidelines for Resuscitation 2015. Resuscitation. 2015;95:202–222.
  7. Krawczyk P, Kołodziej G, Szpyra B, Andres J. Implementation of therapeutic hypothermia after cardiac arrest in intensive care units in Poland. Kardiol Pol. 2013;71:270–274.
  8. Kozinski M, Pstragowski K, Kubica JM, et al. ACS network-based implementation of therapeutic hypothermia for the treatment of comatose out-of-hospital cardiac arrest survivors improves clinical outcomes: The first European experience. Scand J Trauma Resusc Emerg Med. 2013;21:22.
  9. Kowalik R, Szczerba E, Kołtowski Ł, et al. Cardiac arrest survivors treated with or without mild therapeutic hypothermia: Performance status and quality of life assessment. Scand J Trauma Resusc Emerg Med. 2014;22:76.
  10. Zawiślak B, Depukat R, Arif S, Dudek D. Mild induced hypothermia in patient with acute myocardial infarction after cardiac arrest. Kardiol Pol. 2013;71:426–428.
  11. Szymanski F, Karpinski G, Platek A, Puchalski B, Filipiak K. Long QT interval in a patient after out-of-hospital cardiac arrest with hypocalcemia, undergoing therapeutic hypothermia. Am J Emerg Med. 2013;31:1722 e1721–1723. doi: 10.1016/j.ajem.2013.07.026.
  12. Kim JJ, Yang HJ, Lim YS, et al. Effectiveness of each target body temperature during therapeutic hypothermia after cardiac arrest. Am J Emerg Med. 2011;29:148–154.
  13. Shin J, Kim J, Song K, Kwak Y. Core temperature measurement in therapeutic hypothermia according to different phases: Comparison of bladder, rectal, and tympanic versus pulmonary artery methods. Resuscitation. 2013;84:810–817.
  14. Bisschops L, van der Hoeven J, Mollnes T, Hoedemaekers C. Seventy-two hours of mild hypothermia after cardiac arrest is associated with a lowered inflammatory response during rewarming in a prospective observational study. Crit Care. 2014;18:546.
  15. Nielsen N, Wetterslev J, Cronberg T, et al. Targeted temperature management at 33 degrees C versus 36 degrees C after cardiac arrest. N Engl J Med. 2013;369:2197–2206.
  16. Kliegel A, Gamper G, Mayr H. Therapeutic hypothermia after cardiac arrest in Lower Austria - a cross-sectional survey. Eur J Emerg 2011;18:105–107.
  17. Skulec R, Truhlář A, Seblová J, et al. Implementation of pre-hospital therapeutic hypothermia in post-cardiac arrest patients in the Czech Republic. Resuscitation. 2012;83:e21–22.