Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 1.736
5-Year Impact Factor – 2.135
Index Copernicus  – 168.52
MEiN – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
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Advances in Clinical and Experimental Medicine

2016, vol. 25, nr 4, July-August, p. 799–807

doi: 10.17219/acem/32488

Publication type: review article

Language: English

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Photodynamic Therapy As a Promising Method Used in the Treatment of Oral Diseases

Ewa J. Prażmo1,A,B,C,D, Mirosław Kwaśny2,D,E, Mariusz Łapiński2,B, Agnieszka Mielczarek1,C,E,F

1 Department of Conservative Dentistry and Endodontics, Medical University of Warsaw, Poland

2 Institute of Optoelectronics, Military University of Technology, Warszawa, Poland


Photodynamic therapy (PDT) consists of three elements: photosensitizer, light and oxygen. The photosensitizer has the property of selective accumulation in abnormal or infected tissues without causing any damage to the healthy cells. This innovative therapeutic method has already been successfully adapted in many fields of medicine, e.g. dermatology, gynecology, urology and cancer therapy. Dentistry is also beginning to incorporate photodisinfection for treatment of the oral cavity. The antibacterial and fungicidal properties of the photosensitizer have been used to achieve better results in root canal treatment, periodontal therapy and the eradication of candidiasis in prosthodontics. The aim of this article is to discuss the effectiveness of photodynamic methods in the diagnosis and therapy of selected oral diseases. Scientific data and published papers regarding the antibacterial properties of PDT will be subjected to analysis. Photodynamic therapy will be discussed as an alternative treatment protocol in oncology, endodontics, periodontology and other fields of dentistry.

Key words

photodynamic therapy, PDT, photosensitizer, antibacterial therapy

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