Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
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Advances in Clinical and Experimental Medicine

2007, vol. 16, nr 1, January-February, p. 135–139

Publication type: review article

Language: Polish

Autoimmunologiczne aspekty pokrzywki przewlekłej

Autoimmunologiczne aspekty pokrzywki przewlekłej

Robert Sycz1,, Anna Wolańczyk−Mędrala1,, Wojciech Mędrala1,

1 Katedra i Klinika Chorób Wewnętrznych i Alergologii Akademii Medycznej we Wrocławiu

Streszczenie

Opisano autoimmunologiczne aspekty pokrzywki przewlekłej. Przedstawiono patofizjologiczne znaczenie autoprzeciwciał anty−IgE i przeciw podjednostce α receptora FcεRI w indukcji i podtrzymywaniu objawów chorobowych. Dokonano przeglądu aktualnych danych na temat współistnienia tego schorzenia z autoimmunologicznymi chorobami tarczycy. Omówiono również aspekty diagnostyczne i terapeutyczne tej postaci przewlekłej pokrzywki.

Abstract

In this study we have described the autoimmunological aspects of chronic urticaria. Pathophysiological significance of anti−IgE and anti−FcεRI (alpha subunit) autoantibodies in induction and maintenance of clinical symptoms has been reviewed. We have presented the actual data concerning clinical association of chronic urticaria with autoimmunological thyroid diseases. We have also reviewed diagnostic and therapeutical aspects of this form of chronic urticaria.

Słowa kluczowe

pokrzywka przewlekła, autoprzeciwciała, anty−IgE, anty−FcεRIα

Key words

chronic urticaria, autoantibodies, anti−IgE, anti−FcεRIα

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