Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
5-Year IF – 2.0, IF – 1.9, JCI (2024) – 0.43
Scopus CiteScore – 4.3
Q1 in SJR 2024, SJR score – 0.598, H-index: 49 (SJR)
ICV – 161.00; MNiSW – 70 pts
Initial editorial assessment and first decision within 24 h

ISSN 1899–5276 (print), ISSN 2451-2680 (online)
Periodicity – monthly

Download original text (EN)

Advances in Clinical and Experimental Medicine

2006, vol. 15, nr 5, September-October, p. 761–766

Publication type: editorial article

Language: English

Intestinal Transplantation – an Overview

Przeszczepy jelit – przegląd

Girish L. Gupte1,, Alastair J.W. Millar1,

1 Liver Unit, Birmingham Children’s Hospital, United Kingdom

Abstract

Intestinal transplantation is evolving into a standard of care for children with intestinal failure who no longer can be maintained on PN. Advances in immunosuppression in addition to effective monitoring techniques for opportunistic infections have resulted in achieving improved outcome with less morbidity. This article highlights the evolution of intestinal transplantation and current advances.

Key words

intestinal failure, small bowel transplantation, intestinal failure associated liver disease, intestinal transplant registry

References (30)

  1. Irving M: Intestinal failure. J Gastroenterol Hepatol 2000, 15 Suppl, G26–G29.
  2. Goulet O, Ruemmele F, Lacaille F, Colomb V: Irreversible intestinal failure. J Pediatr Gastroenterol Nutr 2004, 38, 250–269.
  3. Holden C: Review of home paediatric parenteral nutrition on the UK. Br J Nurs 2001, 10, 782–788.
  4. Goulet O, Revillon Y: Intestinal transplantation. Indian J Pediatr 2003, 70, 737–742.
  5. Reyes J, Mazariegos GV, Bond GM, Green M, Dvorchik I, Kosmach−Park B et al.: Pediatric intestinal transplantation: historical notes, principles and controversies. Pediatr Transplant 2002, 6, 193–207.
  6. Grant D, Wall W, Mimeault R, Zhong R, Ghent C, Garcia B et al.: Successful small−bowel/liver transplantation. Lancet 1990, 335, 181–184.
  7. Ruemmele FM, Sauvat F, Colomb V, Jugie M, Jan D, Canioni D et al.: Seventeen years after successful small bowel transplantation: long term graft acceptance without immune tolerance. Gut 2006, 55, 903–904.
  8. Todo S, Tzakis A, Reyes J, Abu−Elmagd K, Casavilla A, Fung JJ et al.: Intestinal transplantation in humans under FK 506. Transplant Proc 1993, 25, 1198–1199.
  9. Grant D, Abu−Elmagd K, Reyes J, Tzakis A, Langnas A, Fishbein T et al.: 2003 report of the intestine transplant registry: a new era has dawned. Ann Surg 2005, 241, 607–613.
  10. Kaufman SS, Atkinson JB, Bianchi A, Goulet OJ, Grant D, Langnas AN et al.: Indications for pediatric intestinal transplantation: a position paper of the American Society of Transplantation. Pediatr Transplant 2001, 5, 80–87.
  11. Kato T, Romero R, Verzaro R, Misiakos E, Khan FA, Pinna AD et al.: Inclusion of entire pancreas in the composite liver and intestinal graft in pediatric intestinal transplantation. Pediatr Transplant 1999, 3, 210–214.
  12. Kato T, Tzakis AG Selvaggi G Madariaga J: Surgical techniques used in intestinal transplantation. Curr Opin OrganTransplant 2004, 9, 207–213.
  13. Sudan DL, Iyer KR, Deroover A, Chinnakotla S, Fox IJ, Jr., Shaw BW Jr. et al.: A new technique for combined liver/small intestinal transplantation. Transplantation 2001, 72, 1846–1848.
  14. Starzl TE, Murase N, Abu−Elmagd K, Gray EA, Shapiro R, Eghtesad B et al.: Tolerogenic immunosuppression for organ transplantation. Lancet 2003, 361, 1502–1510.
  15. Fecteau A, Atkinson P, Grant D: Early referral is essential for successful pediatric small bowel transplantation: The Canadian experience. J Pediatr Surg 2001, 36, 681–684.
  16. De Ville dG, Mitchell A, Mayer AD, Beath SV, McKiernan PJ, Kelly DA et al.: En block combined reducedliver and small bowel transplants: from large donors to small children. Transplantation 2000, 69, 555–559.
  17. Watson RA, Howdieshell TR: Abdominal compartment syndrome. South Med J 1998, 91, 326–332.
  18. Selvaggi G, Levi DM, Kato T, Madariaga J, Moon J, Nishida S et al.: Expanded use of transplantation techniques: abdominal wall transplantation and intestinal autotransplantation. Transplant Proc 2004, 36, 1561–1563.
  19. Pappas PA, Saudubray JM, Tzakis AG, Rabier D, Carreno MR, Gomez−Marin O et al.: Serum citrulline as a marker of acute cellular rejection for intestinal transplantation. Transplant Proc 2002, 34, 915–917.
  20. Lee RG, Nakamura K, Tsamandas AC, Abu−Elmagd K, Furukawa H, Hutson WR et al.: Pathology of human intestinal transplantation. Gastroenterology 1996, 110, 1820–1834.
  21. Abu−Elmagd K, Reyes J, Bond G, Mazariegos G, Wu T, Murase N et al.: Clinical intestinal transplantation: a decade of experience at a single center. Ann Surg 2001, 234, 404–416.
  22. Fishbein TM: The current state of intestinal transplantation. Transplantation 2004, 78, 175–178.
  23. Ziring D, Tran R, Edelstein S, McDiarmid SV, Gajjar N, Cortina G et al.: Infectious enteritis after intestinal transplantation: incidence, timing, and outcome. Transplantation 2005, 79, 702–709.
  24. Bueno J, Green M, Kocoshis S, Furukawa H, Abu−Elmagd K, Yunis E et al.: Cytomegalovirus infection after intestinal transplantation in children. Clin Infect Dis 1997, 25, 1078–1083.
  25. Green M, Bueno J, Rowe D, Mazariegos G, Qu L, Abu−Almagd K et al.: Predictive negative value of persistent low Epstein−Barr virus viral load after intestinal transplantation in children. Transplantation 2000, 70, 593–596.
  26. Reyes J, Mazariegos GV, Bond GM, Green M, Dvorchik I, Kosmach−Park B et al.: Pediatric intestinal transplantation: historical notes, principles and controversies. Pediatr Transplant 2002, 6, 193–207.
  27. Mazariegos GV, Abu−Elmagd K, Jaffe R, Bond G, Sindhi R, Martin L et al.: Graft versus host disease in intestinal transplantation. Am J Transplant 2004, 4, 1459–1465.
  28. Iyer K, Horslen S, Iverson A, Sudan D, Fox I, Shaw B et al.: Nutritional outcome and growth of children after intestinal transplantation. J Pediatr Surg 2002, 37, 464–466.
  29. Sudan D, Horslen S, Botha J, Grant W, Torres C, Shaw BW Jr. et al.: Quality of life after pediatric intestinal transplantation: the perception of pediatric recipients and their parents. Am J Transplant 2004, 4, 407–413.
  30. Testa G, Panaro F, Schena S, Holterman M, Abcarian H, Benedetti E: Living related small bowel transplantation: donor surgical technique. Ann Surg 2004, 240, 779–784.
© Wroclaw Medical University