Advances in Clinical and Experimental Medicine

Title abbreviation: Adv Clin Exp Med
JCR Impact Factor (IF) – 1.736
5-Year Impact Factor – 2.135
Index Copernicus  – 168.52
MEiN – 70 pts

ISSN 1899–5276 (print)
ISSN 2451-2680 (online)
Periodicity – monthly


ACEM monthly editorial duty hour

Once a month our Managing Editor, Marek Misiak, is awaiting you at a Google Meets meeting. He will answer all your questions and clarify problematic issues.

The meeting take place on the first Thursday of each month (beginning in April 2023) between 9:30 and 10:30 CET. You can enter the meeting using the following URL:

The only prerequisite is a Google account – without it you will not be able to log in to the meeting.

The dates of the meetings in 2023 are as follows: April 6, May 4, June 1, July 6, August 3, September 7, October 5, November 2 and December 7.

20th Jubilee Scientific and Training Conference of the Polish Society of Pediatric Nephrology

On behalf of the Scientific and Organizational Committee and the Board of PTNefD, we are pleased to invite you to participate in the 20th Jubilee Scientific and Training Conference of the Polish Society of Pediatric Nephrology, which will be held on May 18–20, 2023 in Wrocław.

The theme of the Conference are urinary tract infections, which are among the most common infectious diseases in children. As usual, the latest achievements in other fields of pediatric nephrology and related fields will also be presented.

The conference will be an opportunity to exchange experiences between doctors of various specialties.

Wrocław is described as a "city of meetings", a friendly city that unites people and ideas and inspires.

We cordially invite you to the meeting in Wrocław, hoping that thanks to your presence it will be interesting and fruitful.


Detailed information and registration at

43. Congress of the Polish Medical Society of Radiology

We cordially invite radiologists, electroradiology technicians, nurses, medical physicists, engineers, students and physicians of other specialties to participate at the 43. Congress of the Polish Medical Society of Radiology, which will be held on 15-17 June 2023 at the Wroclaw Congress Center and the Centennial Hall.

We hope and we are determined to live up to the tradition of our radiological meetings, which are an area of knowledge and experience exchange and serve to show achievements and successes in the field of diagnostic imaging, which is an important field of medicine today.

The event will be an opportunity to discuss new challenges and threats facing modern radiology and diagnostic imaging. More information and the registration form can be found at

See you in Wrocław!

Using bar and line graphs to present statistical data

Figures in scientific publications are critically important because they often show the data supporting key findings. However, small sample size studies rarely include scatterplots, box plots and histograms that allow readers to critically evaluate continuous data. Most papers present continuous data as bar and line graphs. This is problematic, as many different data distributions can lead to the same bar or line graph. The full data may suggest different conclusions from the summary statistics.

This issue is concisely discussed [with examples] in this paper:

It is also worthy to read this paper:

Professor Naomi Hachiya is no longer with us

All members of the Editorial Committee and Editorial Board of Advances in Clinical and Experimental Medicine are deeply saddened by the news of Professor Naomi Hachiya’s passing. She was a member of our Editorial Committee since 2021. On behalf of all abovementioned members, we extend our heartfelt condolences to the family, friends, and loved ones of Professor Hachiya. We know that words can give little consolation to relieve grief but we should like you to know that we too will be grieving for her.

She will be greatly missed, but her legacy will live on for many years to come.


明日知らぬ  わが身と思へど  暮れぬ間の   今日は人こそ  かなしかりけれ


Though I don’t know

What will become of my fate

Today isn’t over yet

I’m grieving


[Ki no Tsurayuki (紀貫之), 870–945]


In deepest sympathy,


Prof. Donata Kurpas



Prof. Wojciech Kosmala

Deputy Editor


members of the Editorial Committee of Advances in Clinical and Experimental Medicine

members of the Editorial Board of Advances in Clinical and Experimental Medicine


Increase of article-processing charge

All original papers and meta-analyses submitted after February 1, 2023, 00:01 CET, and not exempt from article processing charge (APC) will be subject to a higher APC if accepted for publication. The new fee is 990 EUR / 4900 PLN for original papers and meta-analyses. The publication fee for reviews, research-in-progress (RIP) papers and research letters does not change and remains as follows:

700 EUR / 3500 PLN for reviews;

350 EUR / 1750 PLN for research-in-progress (RIP) papers;

350 EUR / 1750 PLN for research letters.

All original papers and meta-analyses submitted until January 31, 2023, 23:59 CET are subject to the previous amount of the fee (700 EUR / 3000 PLN for original papers, met-analyses and reviews, 350 EUR / 1500 PLN for research letters).


Chinese New Year

兔年大吉! 前兔似锦!

During the Year of the Tiger, we published over 100 high-quality scientific papers submitted by Chinese researchers – and we want more! Therefore, we want to encourage you to publish in “Advances in Clinical and Experimental Medicine” – a journal which publishes high-quality original articles, research-in-progress, research letters and systematic reviews and meta-analyses of recognized scientists that deal with all clinical and experimental medicine. The journal is published monthly (12 issues per year) – each issue is released on the last day of the respective month. Most articles are published as ahead of print articles before the scheduled release date of the issue they are assigned to.

We offer professional peer review and linguistic editing, presence in the most important scientific databases (PubMed/Medline, Scopus, Science Citation Index Expanded, Embase etc.), and – last but not least – low APC. Our present impact factor is 1.736 and is steadily rising. We are also an open access journal, so your research would be available for members of scientific community worldwide without any financial or formal barriers.

Join our team of authors and reviewers, and participate fully in global knowledge circulation!


Support from the Ministry of Science and Higher Education

Our journal has received financial support within the “Social Responsibility of Science – Support for Academic Publishing” project based on agreement No. RCN/SP/0584/2021 from the resources of Ministry of Science and Higher Education.

Scientific Social Responsibility programs – Science for All – constitute an important offer for society. They aim at identifying opportunities, supporting dialogue and engaging large groups of stakeholders. Science for All increases the efficiency and effectiveness of activities in science and research areas, implementing the University’s Third Mission.

Not only does Science for All popularize and disseminate science but also stimulates cognitive curiosity and integrate local communities with academia. The Science for All initiatives are supposed to equal educational opportunities and reach those parts of the country where academic and scientific activity has not existed so far.

How to create an account in Editorial System?

The editorial staff of Advances in Clinical and Experimental Medicine is aware that creating an account in the Editorial System [], which we use, i.a., for manuscript and review submission, is not always easy from the perspective of authors and peer reviewers. Therefore, we offer a guideline in PDF linked below, which presents the whole process using screenshots and comments.


Guideline – how to create an account in Editorial System


Should any problems arise, do not hesitate to contact the managing editor of Advances in Clinical and Experimental Medicine – Marek Misiak []. He will establish an account for you and will only need to log in.


Graphical abstracts

Beginning with the 1/2023 issue, the journal Advances in Clinical and Experimental Medicine requires also visual abstracts (also known as graphical abstracts) for papers accepted for publication.

Such abstract is a single, concise, pictorial and visual summary of the main findings of the article. It should be a figure that is specially designed for the purpose, which captures the content of the article for readers at a single glance. Authors must provide an original image that clearly represents the work described in the paper. Graphical abstracts should be submitted as a separate file in the submission system as Figure 0. For ease of browsing, the graphical abstract should have a clear start and end, preferably "reading" from top to bottom or left to right. Try to reduce distracting and cluttering elements as much as possible. No additional text, outline or synopsis should be included. Any text or label must be part of the image file. Please do not use unnecessary white space or a heading “graphical abstract” within the image file. The text within the graphical abstract should be used sparingly. The graphical abstract for a paper should not include data items of any type; all the content should be in a graphical form.

Allowed data formats: for VECTOR graphics (charts, diagrams, etc.) – pdf, eps, ai, cdr (if the graphic was created using MS Office programs, source files of a given program are very helpful: doc, docx, ppt, pptx, xls, xlsx); for BITMAP graphics (photos, screenshots) – tif, jpg, png, bmp (min. 1200 pixels of the base in the drawing with the width of one column and 2400 for the width of two columns). The minimal resolution of tif, jpg and png files is 300 dpi. Regarding text within the graphical abstract, its size should be 12–16 points (smaller fonts will not be legible online).

The editorial office of Adv Clin Exp Med does not offer graphical or DTP services – the authors have to provide graphical abstracts in a finished form. Neither one of the figures from the manuscript (e.g., a graph or diagram) nor a PRISMA diagram cannot simultaneously serve as a graphical abstract).


More on how to prepare visual abstract (with examples):

More on how to prepare graphical abstract, more examples and an online tool to prepare it:

Should any questions arise, do not hesitate to contact the editorial office. Please send the graphical abstracts via e-mail at the e-mail address


Editorial System crash

On August 23, 2022, one of the Editorial System servers crashed. The failure forced the recovery of data from the last backup, which was made on the night of August 18 to August 19.

We hope that due to the weekend time there was a little activity by the editorial office. Unfortunately, all operations performed in the system between 19.08 and 22.08 have to be performed again. Due to the monitoring of system messages, we have information about the submitted manuscripts and reviews at that time - we will notify these authors and reviewers in individual messages.

If you provided a revision of the manuscript or a review between 22:00 GMT on August 18 and 8:00 GMT on August 23, please resubmit it – such action has not been registered in the system and the uploaded files have been lost.

We apologize for the inconvenience caused by this situation.


New call for submissions

Application of stem cells in human medicine – from basic science research to clinical trials

Medicine in the twenty-first century is closely associated with stem cell research, based on advanced in vitro analyzes, the use of model animals, and their application in clinical trials. Experimental research requires understanding the physiological and morphological properties of stem cells and analyzing their ability to divide and differentiate into other cell types. The best-known stem cells are those derived from bone marrow and umbilical cord blood. However, in recent years, stem cells have been discovered in, for example, adipose tissue and Wharton jelly. Stem cells isolated from these tissues, once properly differentiated, are increasingly used for the treatment of bone and neurodegenerative diseases. In recent years, the number of therapies using stem cells has increased significantly. The ability of stem cells to differentiate makes them an increasingly common therapeutic tool in regenerative and reconstructive medicine.

Submission of expression of interest by March 15, 2023

Call for full paper submission – by April 30, 2023

Submission of full paper by June 30, 2023


for more information click the image

New Scopus CiteScore

We proudly inform that our Scopus CiteScore has risen from 2.7 for the year 2020 to 3.0 for the year 2021. This positive change is a results of our constant striving for excellence in scientific publishing – but also of the activity of authors who cite papers published in Advances in Clinical in Experimental Medicine. Thank you so much – this is our joint success!



The editorial office of Advances in Clinical and Experimental Medicine proudly informs that the journal has been accepted into Directory of Open Access Journals (DOAJ) and is indexed in this database. This fact confirms our integrity regarding publication ethics and clear rules for authors.


Research letter

A Research letter is a brief, but scientifically important study which is basically a shorter form of Original paper. The text structure (Background – Objectives – Material and methods – Discussion – Limitations – Conslusions) remains the same. Research letters are peer reviewed and subject to stringent editorial review as well. They are also indexed in all databases, including PubMed and Scopus, and the number of points assigned for such publication is identical as for original papers. But a research letter contains a maximum of 1500 words, as opposed to 3500 words in an original article, and at most 2 tables or figures (2 tables and 2 figures at most in one paper). The number of authors and the number of references are not limited.

It is important to note that:

1) research letters are priority papers in our journal and the waiting time for publication is shorter;

2) the article processing charge is twice lower than that for an Original paper (350 EUR/1500 PLN instead of 700 EUR/3000 PLN). 


Our support for Ukraine

The 19th-century Ukrainian Romantic poet, Taras Shevchenko (1814–1861), wrote this poem in 1845:


Як умру, то поховайте
Мене на могилі
Серед степу широкого
На Вкраїні милій,
Щоб лани широкополі,
І Дніпро, і кручі
Було видно, було чути,
Як реве ревучий…

When I die, let me rest
Buried in a grave
On the wide steppe
In my dear Ukraine,
Where the broad-rimmed fields
And the Dnipro, and cliffs
Are visible, so I can hear
How the roaring roars.


Shevchenko’s “Testament” remains an anthem for Ukrainian national sentiment. It’s a poem of longing, written by a man who is separated from his native rivers, cliffs, and steppe. It shows off the alliterative power of the Ukrainian language.


After a Russian-language Odessa poet, Boris Khersonsky, began to write poems in Ukrainian in solidarity with the 2013–2014 Maidan “Revolution of Dignity,” he wrote a version of “Testament.”


Як умру, то не ховайте
мене на могилi.
Хай несуть мене до неба
полум’янi хвилi.
Хай розвiє сiрий попiл
повiтряна сила,
бо йому, щоб полетiти,
не потрiбнi крила.
Бо нема землi на свiтi,
щоб назвав своею.

When I die, don’t let me rest
Buried in a grave
Let the waves of fire carry
Me up to the sky.
Let the windy powers dispel
The gray ash, let it scatter
For, no wings are necessary
For this ash to fly.
For no land in all the world
Can be called my own.


New materials for authors


How to promote your paper? Useful tips

The research paper has been published – but how to make sure that as many other scholars as possible will read and – preferably – cite it? Our editorial team prepared a set of valuable guidelines, concisely describing what an author can do to boost the impact of an article.

Toolbox for authors

We have prepared a useful tool for the authors of our journal, including guidelines needed while working on a new article. We hope that provided instruction will address any of your concerns. Before uploading a new manuscript, read Stylebook in a Nutshell and get acquainted with all necessary information.

New statistical guidelines

Our statistical editors prepared a set of concise and precise statistical guidelines – we are aware that proper conduct of statistical analyses and presentation of their results can be complex.


Media patronage offer

Our media patronage offer is addressed to organizers of scientific events of any type: conferences, congresses, anniversaries of scientific or professional societies, workshops, meetings etc. Our journal can promote the event and publish papers as its outcome. See our detailed offer in the flyer or contact us for further details.

Media patronage offer – flyer


Ministerial evaluation

We proudly announce that Polish Ministry of Education and Science has increased the number of points assigned to “Advances in Clinical and Experimental Medicine” from 40 to 70 points. This change reflects our constant striving for quality in scientific publishing. The editorial team wants to thank especially the section editors, whose competences and research experience as well as efficient work and commitment have chiefly contributed to this achievement.


Changes in publication rules

Please note that since October 1, 2021 after the article is published as ahead of print, it cannot be changed (which encompasses also affiliations and authors’ order). Such stipulation stems from requirements set by scientific databases in which the papers published in Advances in Clinical and Experimental Medicine are stored.

If the article is already accessible online as registered preprint on any website or in any database, and has been already assigned with a DOI, such information, together with an URL of the registered preprint, has to appear in the cover letter.