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@Article{Laszki-Szcząchor2018-09-28, author={Laszki-Szcząchor, Krystyna and Zwolińska, Danuta and Sobieszczańska, Małgorzata and Tabin, Michał and Polak-Jonkisz, Dorota}, title={Disturbances in intraventricular conduction in children with end-stage renal disease on peritoneal dialysis: A pilot study}, title={Disturbances in intraventricular conduction in children with end-stage renal disease on peritoneal dialysis: A pilot study}, journal={Advances in Clinical and Experimental Medicine}, year={2018}, volume={27}, number={9}, pages={1225--1231}, month={09}, day={28}, publisher={Wroclaw Medical University}, abstract={Background. The progression of chronic kidney disease is accompanied by multi-organ disorders, among which cardiovascular diseases have the status of a serious clinical problem. The body surface potential mapping (BSPM) technique is a non-invasive method which enables the detection of pathological changes in the bioelectrical activity of the heart.Objectives. The aim of this study was to identify possible disturbances in the intraventricular conduction system in peritoneally dialyzed children.Material and Methods. Cardiac examination consisted of 12-lead electrocardiography, echocardiography and BSPM. The evaluation of disturbances in the cardio-electrical field was performed by comparing the qualitative and quantitative features of the heart potentials on the isopotential map.Results. Data was collected from 10 children treated with automatic peritoneal dialysis (APD) (mean age: 13.6 ±2.3 years) and 26 healthy children. The maps of dialyzed children showed a shift in positive isopotentials toward the left lower part of the thorax, while negative values were observed in its left upper part. A distribution of lines on the isopotential maps revealed disturbances in the stimulation spread within the heart ventricles, especially within the anterior fascicle of the left bundle branch of His.Conclusion. Intraventricular conduction disturbances were observed in the left bundle branch of His in the peritoneally dialyzed children. The body surface potential mapping was a more sensitive method in identifying the early stage of conduction disturbances within the heart ventricles than 12-lead electrocardiography. Further research involving a larger population of dialyzed children is planned.}, issn={1899-5276}, doi={10.17219/acem/69255}, url={http://dx.doi.org/10.17219/acem/69255},